![]() ![]() There is one important exception to this: antibiotics, especially those in the penicillin, cephalosporin and tetracycline classes.Many of them will remain unchanged for dozens (hundreds?) of years. By far, most drugs are extremely stable, especially in capsule and tablet form. ![]() He provides information that is somewhat different, and more detailed than the WSJ article: Bloom, whose specialty is quality control and drug stability. ![]() ![]() Perhaps the most helpful information about this comes from a former colleague of Dr. Even the slightest decomposition of aspirin will give this smell, even though the aspirin may still be 99+% pure. This is true one of the breakdown products of aspirin is acetic acid (vinegar). We have been told forever that when aspirin decomposes, it smells like vinegar. This is a property of the drug itself not an indication that there is anything wrong. For example, the antibiotic amoxicillin has an awful, sulfur-like smell. Bloom says, Number three is not necessarily true.
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